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This site acts as a hub to bring all the key information and journals on vitamin B12 deficiency together in one place. It originates in the UK and holds information particular to the NHS, however, my aim is to give a direct route to factual information, wherever you are in the world. None of the information contained within this site is hidden behind paywalls.


The main aim of the site is to help patients to gain a greater understanding of the condition, to acheive a correct diagnosis and correct treatment from their doctor. Education is the key, if you want to learn more please see our conference page.

All pink text throughout the site will take you to journals or further reading.

If you think you are B12 deficient please visit the What to do next? page. There is also a page to help with writing to your doctor should the need arises.

I would like to take this opportunity to express my sincere thanks to both Sally M. Pacholok R.N. and Pat Kornic for their support in creating this website. Click here for Pat's support group.

Sally Pacholok is a name recognised around the world for the excellent book 'Could it be B12?'  Co authored with her husband Dr. Jeffrey Stuart, this book's 1st edition was published in 2005 and has saved many lives. Text from the book is used with permission throughout this site. An award winning feature film has been made based on Sally's life you can now download the film from Vimeo.

Issues that patients face

  • Failure of healthcare professionals to recognise the neurological and psychiatric symptoms of B12 deficiency.

  • The name ‘Pernicious anaemia’ confuses doctors - many patients NEVER present with anaemia/macrocytosis - this is very late stage. NICE and BNF Guidelines still categorise B12 deficiency under anaemia, this needs to change. 

  • Poor Diagnostic tests and reference ranges of B12 serum test range set so low missing severely deficient patients.

  • The misconception that B12 deficiency is rare and only affects women over 60. In fact it is very common affects all body systems, all ages and both sexes

  • Lack of understanding of the many causes of B12 deficiency and those at risk leading to misdiagnoses

  • Harmful maintenance dosage guidelines which restrict the vast majority of UK patients to just 4 B12 injections per year. There is no clinical evidence held by the Marketing Authorisation Holders or the BNF for the restricted treatment regime for UK patients, this is based upon cost saving GP Audits and not care for the patient.

  • The misconception that B12 injections are a placebo and that too much is toxic. B12 is a water soluble vitamin and any excess is excreted quickly via the bladder and bowel.

  • Reliance on flawed B12 serum test results rather than symptoms can lead to permanent damage.

  • Incorrect treatment of neurological symptoms with oral B12 instead of vital B12 injections leads to irreversible damage.  

  • Lack of understanding of the genetictransport and methylation defects affecting B12 absorption and metabolisation


Below is a short film made for a petition which asks the Department of Health for testing for B12 deficiency to be added to a Full Blood Count. To sign and share the petition please click here.

Simply watching the first 5 minutes of this documentary film will make it clear just how serious B12 deficiency is and how misdiagnosis can occur. The education of all clinicians on this very common condition is critical.


Many with this condition feel they have no alternative but to resort to self treatment. They purchase their injectable B12 from the many countries where it is legally sold over the counter. Faced with doctors who refuse to treat patients adequately, self injecting is often the only route to health. If we could buy injectable B12 over the counter in the UK it would change lives, please sign the petition below.


Thank you for visiting the site.



Tracey Witty, a patient living with B12 deficiency.



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